Orin
DGXNYSE·Medical - Diagnostics & Research

Quest Diagnostics Incorporated DGX

Market cap $25.9BP/E 24.4× trailingGross margin 33.1%Reports Tue 20 Oct, before the open
$234.61
+1.61 (+0.69%)live 09:40 ET
52-wk $171.18 – $248.84
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Orin's take
0.62conviction · moderate
Refreshed 31 Aug · take v7. A new filing or a print queues the next refresh.

Quest Diagnostics posted strong FY2025 results with revenue of $11.04B (+11.8% YoY), EPS of $8.75 (+13.8% YoY), and FCF of $1.36B versus $909M in FY2024, while operating margin expanded from 13.63% to 14.53%. However, gross margin compressed for a third consecutive year to 31.93% (from 32.86% in FY2024 and 33.17% in FY2023), and the stock is trading near its 52-week high of $246 at $240.30 with EV/EBITDA of 16.08x slightly above the peer median of 15.76x.

With net insider selling of $15.7M over 24 months and a modest smart money score of 0.0073 as of the quarter ended 2026-06-30, the fundamental improvements are largely reflected at current levels.

What could go wrong

  • Gross margin erosion. Gross margin has compressed for three straight years to 31.93% in FY2025 from 32.86% in FY2024 and 33.17% in FY2023, signaling pricing or cost pressures that could eventually weigh on operating leverage.
  • Elevated leverage. Total debt of $6.92B against stockholders' equity of $7.17B as of FY2025 leaves limited balance sheet flexibility for further M&A or buybacks without additional leverage.
  • Insider selling. Net insider selling of $15.7M over the trailing 24 months with 109 dispositions versus 107 acquisitions, including recent option exercise-and-sell transactions by the SVP & General Counsel on 2026-08-28.
  • Reimbursement and regulatory headwinds. A Zacks article dated 2026-08-21 flagged debt and reimbursement risks despite growth across key channels and advanced diagnostics.

What would change my mind

Gross margin stabilization. Q3 2026 results show gross margin holding at or above 32%, reversing the three-year compression trendbullish
Revenue deceleration. Quarterly revenue growth slows below high single digits, indicating the FY2025 acceleration was driven by one-time factorsbearish
Debt reduction. Total debt declines meaningfully below $6.5B through free cash flow deployment, improving balance sheet flexibilitybullish

Where this comes from: FMP annual fundamentals, FY2025 · FMP annual fundamentals and derived_metrics, FY2025 · FMP annual fundamentals, FY2025 and FY2024 · Derived metrics, FY2023–FY2025. Orin's read on DGX; not advice.

Twelve months actual closes to 2026-09-23 · actual filings

Sept 25Nov 25Jan 26Mar 26May 26Jul 26

50-day average 200-day average · volume below

Largest holders · 13F Q2 2026

Money flow
FilerPositionOf fund
Vanguard Capital Management$1.5B0.0% of fund
Vanguard Portfolio Management$1.3B0.1% of fund
State Street$1.2B0.0% of fund
Price T Rowe Associates /Md/$1.2B0.1% of fund
Jpmorgan Chase &$748.6M0.0% of fund
Geode Capital Management$662.6M0.0% of fund

89 filers · quarter ended Q2 2026 · positions, not flows

Insiders, last 24 months: 217 Form 4 filings, net −$18.2M. Of the 50 on hand, 0 were open-market purchases and 10 sales— the rest are grants, option exercises and tax withholding.

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Where it trades

vs its own 5y · Healthcare
MetricNowOwn medianSector
P/E24.4×19.2×26.4×
EV/EBITDA15.7×11.7×
P/S2.22×1.75×
P/B3.4×2.7×

Its P/E sits above all 5 of the last 5 years (+2.15σ from its own mean).

What the price assumes

7.0%

free-cash-flow growth every year for 10 years, discounted at 10%, is what today’s price implies — starting from $1.4B of trailing free cash flow. It is an assumption the market is making, not a forecast Orin is making.

What Wall Street published

34 firms · 2026-09-23
Consensus target

$249

$225$260 · +6% against today's price

How they rate it
  • 13 buy or overweight
  • 18 hold
  • 3 underweight or sell

The analysts’ consensus and their own ratings, not Orin’s. A target is a twelve-month opinion published by the firm that wrote it.

Against the companies it is compared to

median P/E 25.0× of 5 peers
CompanyMarket capP/EEV/EBITDAGrossNetROE
DGXQuest Diagnostics Incorporated$26B24.4×15.7×33.1%9.2%14%
INCYIncyte Corporation$25B15.3×10.4×92.6%27.7%30%
LHLabcorp Holdings Inc.$25B25.0×14.7×27.8%7.0%12%
WATWaters Corporation$41B104.6×51.4×50.8%3.6%2%
WSTWest Pharmaceutical Services, Inc.$26B47.8×32.0×36.8%17.0%19%
ZBHZimmer Biomet Holdings, Inc.$18B22.0×12.6×69.9%9.5%6%

The median is of the 5 peers listed above and nothing else — check it against the column. This company trades 2.2% below it. The peer set is the vendor’s, so a company can appear here that a person would not have chosen.

What it has traded at

P/E by fiscal year
FY14 17.5×FY25 19.6×

What its sector has traded at

Healthcare
FY14 6.5×FY26 28.6×

Two scales, drawn separately on purpose: a sector median and one company’s multiple are not the same number and putting them on one axis invites a comparison neither series supports.

Discounted cash flow

not recomputed since
ModelFair valueAgainstComputed
Standard DCF$219$203.79 · +7%2026-06-10
Levered DCF$223$203.79 · +10%2026-06-10

The vendor’s intrinsic-value models. Treat them as a low-growth anchor — for a fast grower the market routinely pays well above a DCF. These were computed against the price in the “against” column, not today’s.

Every estimate on one scale

price $234.61
52-week range$171 – $249
Analyst targets$225 – $260
Standard DCF$219 as of 2026-06-10, when it was $203.79
Levered DCF$223 as of 2026-06-10, when it was $203.79
At own 5y-median P/E (19×)$183
At 5y P/E range (11–19×)$103 – $185
At sector P/E (26×)$252

The vertical rule is the current price. Ranges and point estimates are the backend’s, published as they were calculated; an arrow means the estimate sits beyond this scale, and its number is on the right.