Orin
MRNANasdaq·Biotechnology

Moderna, Inc. MRNA

Market cap $71.8BP/E no earnings to divide byGross margin -12.6%Reports Thu 5 Nov, before the open
$180.96
−1.15 (−0.63%)live 09:30 ET
52-wk $22.28 – $192.31
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Orin's take
0.62conviction · moderate
Refreshed 18 Aug · take v6. A new filing or a print queues the next refresh.

The FDA approval of mFlusiva on August 6, 2026 gives Moderna its first non-COVID commercial product, and the stock's technicals have improved meaningfully since the prior sell call—last close $64.46 sits above both the 50-day MA ($61.06) and 200-day MA ($46.67), with a bullish MACD histogram of +1.02. However, FY2025 fundamentals remain deeply impaired: revenue fell 39.2% YoY to $1.944B against a $2.822B net loss and $2.065B FCF burn, and at a P/S of 11.48 the stock trades at a 23% premium to profitable peer TECH (9.33) despite massive losses.

The flu vaccine approval is a genuine catalyst but is insufficient to justify the valuation given ongoing cash destruction, making this a hold pending evidence of commercial traction and cash burn moderation.

What could go wrong

  • Cash burn trajectory. FY2025 free cash flow burn of $2.065B against stockholders' equity of $8.65B (down from $10.9B in FY2024) and rising total debt of $1.916B raises runway concerns if revenue does not recover.
  • Competitive flu vaccine market. mFlusiva enters a crowded seasonal flu vaccine market for adults 50+; commercial uptake and pricing power are unproven.
  • Pipeline setbacks. The prior norovirus Phase III miss illustrates binary clinical risk; additional late-stage failures in oncology or rare disease programs would remove remaining pipeline optionality.
  • Insider selling pressure. Over 24 months, insider net value is -$16.6M across 241 transactions; CEO Bancel exercised options at $19.15 and sold shares at $56–58 in August 2026, signaling limited insider conviction at current levels.

What would change my mind

Q3 2026 revenue and flu contribution. Quarterly revenue demonstrates material contribution from mFlusiva and approaches or exceeds growth guidance, signaling commercial inflectionbullish
Pipeline readout failure. A key late-stage oncology or rare disease trial misses primary endpoints, removing pipeline catalysts and collapsing the valuation premiumbearish
Cash raise or dilution. Moderna announces a secondary offering or convertible debt issuance to fund operations, signaling runway stressbearish

Where this comes from: news articles published 2026-08-06 (Benzinga, Barrons, Fast Company) · FMP fundamentals FY2025; derived_metrics revenue_growth_yoy -0.3923 · FMP fundamentals FY2025 · peer_relative composite. Orin's read on MRNA; not advice.

Twelve months actual closes to 2026-09-23 · actual filings

Sept 25Nov 25Jan 26Mar 26May 26Jul 26

50-day average 200-day average · volume below

Largest holders · 13F Q2 2026

Money flow
FilerPositionOf fund
Fmr$3.6B0.2% of fund
Vanguard Capital Management$1.6B0.0% of fund
Capital World Investors$1.6B0.2% of fund
State Street$1.1B0.0% of fund
Vanguard Portfolio Management$1.1B0.0% of fund
Geode Capital Management$678.8M0.0% of fund

82 filers · quarter ended Q2 2026 · positions, not flows

Insiders, last 24 months: 287 Form 4 filings, net −$36.5M. Of the 50 on hand, 0 were open-market purchases and 5 sales— the rest are grants, option exercises and tax withholding.

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Where it trades

vs its own 5y · Healthcare
MetricNowOwn medianSector
P/S32.43×5.55×
P/B10.7×2.7×

Its P/E sits below all 5 of the last 5 years (−3.28σ from its own mean).

What Wall Street published

29 firms · 2026-09-23
Consensus target

$116

$25$245 · −36% against today's price

How they rate it
  • 8 buy or overweight
  • 16 hold
  • 5 underweight or sell

The analysts’ consensus and their own ratings, not Orin’s. A target is a twelve-month opinion published by the firm that wrote it.

Against the companies it is compared to

median P/E 62.0× of 1 peers
CompanyMarket capP/EEV/EBITDAGrossNetROE
MRNAModerna, Inc.$72B-12.6%-141.4%-39%
TECHBio-Techne Corporation$11B62.0×33.1×65.8%15.0%9%

The median is of the 1 peers listed above and nothing else — check it against the column. The peer set is the vendor’s, so a company can appear here that a person would not have chosen.

What it has traded at

P/E by fiscal year
FY21 8.4×FY22 8.4×

What its sector has traded at

Healthcare
FY14 6.5×FY26 28.6×

Two scales, drawn separately on purpose: a sector median and one company’s multiple are not the same number and putting them on one axis invites a comparison neither series supports.

Discounted cash flow

not recomputed since
ModelFair valueAgainstComputed
Standard DCF$-2$46.32 · −104%2026-06-10
Levered DCF$-3$46.32 · −107%2026-06-10

The vendor’s intrinsic-value models. Treat them as a low-growth anchor — for a fast grower the market routinely pays well above a DCF. These were computed against the price in the “against” column, not today’s.

Every estimate on one scale

price $180.96
52-week range$22 – $192
Analyst targets$25 – $245
Standard DCF$-2 as of 2026-06-10, when it was $46.32
Levered DCF$-3 as of 2026-06-10, when it was $46.32

The vertical rule is the current price. Ranges and point estimates are the backend’s, published as they were calculated; an arrow means the estimate sits beyond this scale, and its number is on the right.